Wednesday, December 26, 2012

Tuesday, December 25, 2012

A prospective study in detection of lower-limb lymphedema and evaluation of quality of life after vulvar cancer surgery.


A prospective study in detection of lower-limb lymphedema and evaluation of quality of life after vulvar cancer surgery.


Jul 2012

Source

Department of Obstetrics and Gynaecology, 2nd Medical Faculty of Charles University in Prague, Czech Republic. marta.novackova@seznam.cz

Abstract


BACKGROUND:

Lower-limb lymphedema is one of the most disabling adverse effects of vulvar cancer surgery. Multifrequency Bioelectrical Impedance Analysis (MFBIA) is a modern noninvasive method to detect lymphedema. The first aim of this study was to prospectively determine the prevalence of secondary lower-limb lymphedema after surgical treatment for vulvar cancer using objective methods, circumference measurements and MFBIA technique. The second aim was to compare quality of life (QoL) before and 6 months after vulvar surgery.

METHODS:

Twenty-nine patients underwent vulvar cancer surgery in our study: 17 underwent inguinofemoral lymphadenectomy (RAD), and 12 underwent sentinel lymph node biopsy (CONS). Patients were examined before and 6 months after vulvar surgery by measuring the circumference of the lower limbs and with MFBIA. A control group of 27 healthy women was also measured. To evaluate QoL, the European Organisation for Research and Treatment of Cancer (EORTC) QoL questionnaires (QLQ-C30 and QLQ-CX24) were administered to patients before and 6 months after surgery.

RESULTS:

Using circumference measurement, 9 lymphedemas (31%) were diagnosed: 3 (25%) in the CONS and 6 (37.5%) in the RAD group (P = 0.69). After vulvar surgery, patients in the RAD group reported more fatigue and worsening of physical and role functioning. When comparing both groups, the RAD group had significantly worse parameters in social functioning, fatigue, and dyspnea.

CONCLUSIONS:

Lower radicality in inguinofemoral lymphadenectomy shows a trend toward lower morbidity and significantly improves QoL. Multifrequency Bioelectrical Impedance Analysis was tested in these patients as a noninvasive, objective method for lymphedema detection. Detection of lymphedema based on subjective evaluations proved to have an unsatisfactory sensitivity. Less radical surgery showed objectively better results in QoL.

Distichiasis-lymphedema syndrome with optic disc pit


Distichiasis-lymphedema syndrome with optic disc pit


Leg Lymphedema

Jan-Feb 2011

Indian J Ophthalmol. 2011 Jan-Feb; 59(1): 71–72.


Dear Editor,
An eight-year old boy, first born to third degree consanguineous parents, presented with right leg swelling for three months, with gradual onset, which progressed up to knee. There was no history of fever, injury, abdominal pain or contact with tuberculosis. He was treated with anti-filarial drugs elsewhere. At two years of age, he had frequent episodes of redness and constant rubbing of eyes and was then diagnosed to have double-rowed eye lashes involving all four eyelids and the extra rows of lashes were cauterized and removed elsewhere. The boy still continued to be symptomatic. None of the other family members had similar complaints.
On examination, he had right lower limb edema, which was from the knee downward.  There were no bony deformities or vertebral anomalies. Systemic examination was normal. He had mild congestion of both eyes. His visual acuity was 20/20; N6 in both eyes, and had no refractory error. Slit-lamp examination revealed distichiasis.  focal area of loss of eyelashes and depigmentation of skin was noted in the left upper eyelid. Fundus examination revealed an optic disc pit in the left eye and the macula was normal
Blood parameters were normal. Night smears for microfilaria were negative. Ultrasonography (USG) abdomen, echocardiogram, magnetic resonance imaging (MRI) spine, and vascular Doppler studies of both limbs were normal. Isotope lymphoscintigraphy confirmed the lymphedema. The parents were also screened and found to be normal. A clinical diagnosis of distichiasis-lymphedema syndrome (DLS) was made. Conservative management for symptomatic distichiasis, with lubrication and epilation was carried out, advice for Amsler test at home periodically and stockings for lymphedema were given. The parents were genetically counseled for prevention of secondary complications such as, cellulitis, foot infections, and varicose veins.
Figure 1
Full Text Article:

Thursday, December 20, 2012

Lymph nodes of the foot

Lymph nodes of the foot

Lymph supply of the feet



Bellissimabeauty

Lymph supply of the feet




3d4 Medical



ClipArt

See also:

Lymph nodes

Popliteal lymph nodes

Popliteal lymph nodes - located in the knee area

The small popliteal lymph nodes are four or five in number and surround the popliteal veins and arteries. They are clustered at the back part of the leg behind the knee joint. They help collect excess fluids from your feet and legs.




  • Popliteal artery and its branches
  • Popliteal vein and its tributaries
  • Tibial and common peroneal nerves.
  • Termination of the small saphenous vein.
  • Lower part of the posterior cutaneous nerve of the thigh.
  • Popliteal lymph nodes, connective tissue and fat.


Organatomy




King Saud University




Dartmouth

Leg and Inguinal Lymph Nodes


The inguinal nodes - groin area.  I had a lymphangiogram done in 1966 and a lymphoscintigraphy done in 2006 - and they showed me missing significant numbers of inguinal nodes.  In 1962, when I was nine years old, I had an inguinal node removed due to necrosis from cellulitis - in left leg.

In 2000, I had a small needle biopsy on an inguinal node in the right leg.  Yep....it was positive.

In 1995, I was diagnosed with mixed b-cell lymphoma.







Wellsphere




Plymouth Hospitals



Lymphedema People

Lymph nodes - female. Though the abdominal nodes will be different due to different organs, the inguinal nodes remain the same.



Healthtap



Hopkins

Thursday, December 13, 2012

Lymphoscintigraphy in unilateral lower limb and scrotal lymphedema caused by filariasis.


Lymphoscintigraphy in unilateral lower limb and scrotal lymphedema caused by filariasis.


Dec 2012

Source

Department of Nuclear Medicine and PETCT, Amrita Institute of Medical Sciences, Cochin, Kerala, India.

Abstract


Lymphedema is the edema that results from chronic lymphatic insufficiency. Lymphatic filariasis is caused by the filarial nematodes Wuchereria bancrofti, Brugia malayi, and Brugia timori. Lymphatic filariasis is common in tropical and subtropical regions. Early diagnosis and prompt therapy can be implemented using lymphoscintigraphy. Our patient is a 15-year-old boy presenting with a 3-month history of hydrocele. The patient was referred to us to rule out any lower limb lymphatic obstruction as the patient is from an endemic area. Tc Sulfur colloid (filtered) lymphoscintigraphy showed abnormal tracer collection in the scrotum and penis. There is associated dermal backflow or stasis in the left thigh region extending just above the knee, suggesting partial obstruction of left inguinal lymphatic channels.


See also: