Showing posts with label pain. Show all posts
Showing posts with label pain. Show all posts

Sunday, November 25, 2012

Secondary Leg Lymphedema

Secondary Leg Lymphedema


Related terms: leg swelling, leg edema, leg lymphoedema
Introduction
If you ask most people that are familiar with lymphedema the question, “Are you aware of secondary lymphedema,” most would reply that “yes, it is where the arm swells after the lymph system has been damaged by breast cancerbiopsy and treatment.” This is called arm lymphedema.
Even if they are aware that such a condition as secondary leg lymphedema exists, their response might well be that it is a small group of afflicted men who have prostate cancer.
Thus shows how little awareness there is about this particular form of lymphedema. Even in the lymphedema world it is a poor step-child.
However, if the membership of Lymphedema People and the posts in the online lymphedema support groups are an indication, this condition is increasing dramatically.
The reasons for this increase are multiple. They include:
1. increased survival rates of cancer 2. improved treatment of trauma injuries that previously would have been terminal 3. increase in antibiotics for infections and treatment for other conditions that previously might have resulted in death.
It is also important to note that secondary leg lymphedema does not necessarily start immediately after the injury or trauma. It may not start for years.
What is secondary leg lymphedema?
Secondary lymphedema is a condition where the lymphatic system has been damaged. The main job of this system is to move excess through and out of our bodies. When it becomes damaged or impaired, it is no longer able to accomplish this function and these fluids (lymph fluids) collect in the interstitial tissues of our legs. This causes leg swelling.
Another important function of the lymph system is to help our bodies fight infections. With lymphedema, this ability is also weakened and the patient becomes more susceptible to infections.
What causes secondary leg lymphedema?
Secondary leg lymphedema (also referred to as acquired lymphedema) is caused by or can develop as a results of:
1.) Surgeries involving the abdomen or legs where the lymph system has been damaged. This includes any intrusive surgery.
Examples are
vein stripping surgery for peripheral vascular disease hip replacement knee replaement insertion of bolts, screws and other devices in orthopaedic repair lipectomy
2.) Removal of lymph nodes for cancer biopsy. These cancers include, but are not limited to
3.) Radiation treatment of these cancers that scars the lymph system and lymph nodes
4. Some types of chemo therapy. For example, tamoxifen has been linked to secondary lymphedema and blood clots.
5.) Severe infections/sepsis. Generally referred to as lymphangitis, this is a serious life-threatening infection of the lymph system/nodes.
6.) Trauma injuries such as those experienced in an automobile accident that severly injures the leg and the lymph system.
7.) Burns - this even includes severe sunburn. We have a member that acquired secondary leg lymphedema from this.
8.) Bone breaks and fractures.
9.) Morbid obesity - the lymphatics are eventually crushed by the excessive weight. When that occurs, the damage is permanent and chronic secondary leg lymphedema begins.
10.)Insect bites
What are some of the symptoms of secondary leg lymphedema?
These symptoms may include:
1.) Unexplained swelling of either part of or the entire leg. In early stage lymphedema, this swelling will actually do down during the night and/or periods of rest, causing the patient to think it is just a passing thing and ignore it.
2.) A feeling of heaviness or tightness in the leg
3.) Increaseing restriction on the range of motion for the leg.
4.) Unsual or unexplained aching or discomfort in the leg.
5.) Any change involving hardening and/or thickening of the skin or areas of skin on the leg.

Thursday, September 20, 2012

Diagnosis and treatment of venous lymphedema.


Diagnosis and treatment of venous lymphedema.


Jan 2012

Source

The Rane Center, Flowood, MS. USA. rajumd@earthlink.net

Abstract


BACKGROUND:

Chronic venous disease (CVD) is a common cause of secondary lymphedema. Venous lymphedema is sometimes misdiagnosed as primary lymphedema and does not receive optimal treatment. We have routinely used intravascular ultrasound (IVUS) imaging in all cases of limb swelling. The aim of this study is to show that (1) routine use of IVUS can detect venous obstruction missed by traditional venous testing, and (2) iliac-caval venous stenting can yield satisfactory clinical relief and can sometimes reverse abnormal lymphangiographic findings.

METHODS:

The study comprised CVD patients who underwent iliac vein stenting. Lymphangiography was abnormal in 72 of 443 CEAP C(3) limbs, with leg swelling as the primary complaint (abnormal lymphangiography group). Clinical features and stent outcome were compared with a control group of 205 of 443 with normal lymphangiography (normal lymphangiographic group).

RESULTS:

Clinical features were a poor guide to the diagnosis of lymphedema. Isotope lymphangiography was not helpful in differentiating primary from secondary lymphedema. Venography had 61% sensitivity to the diagnosis of venous obstruction. IVUS had a sensitivity of 88% for significant (50% area stenosis) venous obstruction. At 40 months, cumulative secondary stent patency was similar for the abnormal (100%) and normal lymphangiographic (95%) groups. Swelling improved significantly after stent placement in the abnormal lymphangiographic group (mean [standard deviation] swelling grade improvement 0.8 ± 1.1) but was less  than in the control group. 

Complete swelling relief was 16% and 44% and partial improvement  was 45% and 66%  in the abnormal and normal lymphangiographic groups, respectively. 

Associated pain was present in 50% and 36% of the swollen limbs in the abnormal and normal lymphangiographic groups. Pain relief at 40 months was 87% and 83%, respectively (P = .3), with 65% and 71%, experiencing complete pain relief. Quality of life criteria improved after stent placement in both groups but to a better extent in the normal lymphangiographic group. Abnormal lymphangiography improved or normalized in 9 of 36 (25%) of those tested after stent correction.

CONCLUSIONS:

Prevailing practice patterns and diagnostic deficiencies probably result in the misdiagnosis of many cases of venous lymphedema as "primary" lymphedema. IVUS is recommended to rule out venous obstruction as the associated or initiating cause of lymphedema. Iliac venous stenting to correct the obstruction has excellent long-term patency and good clinical outcome, although results are not as good as in those with normal lymphatic function.